Polysaccharide-Targeting Nanoantibiotics: A New Approach to Kill Gram-Negative Superbugs

Enhanced Nitric Oxide Delivery Through Self-Assembling Nanoparticles for Eradicating Gram-Negative Bacteria

X Lai, L Yu, X Huang, W Gardner, SE Bamford, PJ Pigram, S Wang, APL Brun, BW Muir, J Song, Y Wang, HY Hsu, PWH Chan, HH Shen

2024-12-27

In the current battle against antibiotic resistance, the resilience of Gram-negative bacteria against traditional antibiotics is d..

Cholic-Acid Derived, Guanidine-Functionalized Polymers as Broad-Spectrum Antimicrobial Agents

Y Xiong, U Nayanathara, X Lai, X Huang, C Zhang, D Yuen, P Sangwan, HH Shen, APR Johnston, BW Muir, GK Such

2024-12-10

In this study, we report the design of a new guanylated, cholic-acid-based monomer (GM) to combat antimicrobial resistance. The mi..